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FoldSeek

Some types of search, such as by sequence or structure similarity, require specialized tools. Foldseek is a fast and reliable protein structure similarity lookup algorithm.

How to Use FoldSeek​

Find others like 3kwd

FoldSeek runtimes scales with the size of the database used. Typically 0.5 to 1.0 min on the PDB.

Inputs​

PDB File
Protein structure file.
Database

A specific database to search against. Copilot currently uses PDB as the default.

Outputs​

List of Hits
A list of database hits, structurally aligned to the input.
TM-Score

Score of structural identity between two proteins. Ranges from 0.0 to 1.0, with 0.0 being no match, 1.0 being exact match, and 0.5 being same fold/family.

Fident

Percentage sequence identity between the database hit and input after structural alignment. 100 means identical sequence match.

Examples​

Find similar proteins to MA998

Lookup structures like P42212

GFP