M8E3Q

Prompt

Lipoprotein localization refers to the process by which lipoproteins are directed to specific locations within a cell, while cellular localization describes the distribution of various molecules or organelles within different areas of the cell.

AI Generated Sequence

227 AAs | 24.98 kDa | 26.8 kDa (with tag)

MSALELRGLRRYRGGEREEVVVRGVSLSIEAGEVVAIVGESGSGKSTMGFVQELLDTPSEGSVLLDGEEVEELSEEERALARREEVGFVYQFHLLPEGMTALENVAMPALILGVRRPEAEERAEELLERLGVGERLEHRPGEQSGGIRQRVAIARALMGEGEIVLADEPTGALDPRTAAQVMELLFEVARERGRTVVIVTHDMEIAEMADRILRMEGERVADVELLE

Ligand/Cofactor

Adenosine triphosphate

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Computational Metrics

PLDDT

GPT Score

39.32

AAComp

84.15

DiffDock Confidence

-1.2

Seqdif (SeqID)

54.05 (HEV8678555)

Structdif (F-Target)

93.96 (2pcj B)

ProtNLM

Name	Score
Lipoprotein-releasing system ATP-binding prote...	0.296
7.6.2.-	0.233
ABC transporter ATP-binding protein	0.171
ATP-binding cassette domain-containing protein	0.041
3.6.3.-	0.039
Lipoprotein-releasing system ATP-binding protein	0.032
ABC transport system ATP-binding protein	0.025
Macrolide ABC transporter ATP-binding protein	0.024
ABC transporter	0.016
ABC-type antimicrobial peptide transport syste...	0.012

Experimental Results

Company	Variant	Expression System	Concentration (mg/ml)	Total Yield (µg)	Purity (%)	TM (°C)	Tm(oC w/2mM AMP-PNP)
Tierra	T3	Enzyme Optimized System	0.45 (Lunatic)	22.5	100	N/A	N/A
Tierra	T4	Enzyme Optimized System	0.58 (Lunatic)	29	100	N/A	N/A
Tierra	T3	Biologics Optimized System	0.36 (Lunatic)	18	100	N/A	N/A
Tierra	T4	Biologics Optimized System	N/A	N/A	N/A	N/A	N/A
Arctoris	N/A	E. coli	N/A	N/A	N/A	N/A	N/A

Data

34atp_-0.86t | 26