MGT2P

Prompt

1.2.5.1

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With a quinone or similar compound as acceptor. pyruvate dehydrogenase (quinone).

AI Generated Sequence

282 AAs

MKQTVAALIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMHTRHEEVAAFAAGAEAQLTGELAVCAGSCGPGNLHLINGLFDAHRSHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQMPRVLAIAMRKAILNRGVSVVVIPGDVALKAAPADAVTPWYHAPLPVVTPAEEDLRKLADLLRYSKNIAMLCGSGCAGAHDEVVEFAATLKAPVVHALRGKEHVEYDNPFDVGMTGLIGFSSGYHAMMNADTLLMLGTQFPYRAFY

Ligand/Cofactor

pyruvate

CC(=O)C(=O)[O-]

Validation Metrics

PLDDT	90.0
NLMSIM	70.0
AACOMP	93.9
Seqdif (SeqID)	11.0 (MCO9892738.1)
Structdif (F-Target)	3.3 (3eya G)

ProtNLM

Name	Score
Ubiquinone-dependent pyruvate dehydrogenase	0.418
1.2.5.1	0.177
Pyruvate dehydrogenase	0.137
Pyruvate oxidase	0.086
Pyruvate:ubiquinone-8 oxidoreductase	0.050
Pyruvate dehydrogenase (Quinone)	0.039