MHQOR

Prompt

1.1.1.81

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. hydroxypyruvate reductase.

AI Generated Sequence

326 AAs

MKPSVVLYKAIPADLLARLAQHFTVTQFNGLTPDTQPELLAAQGQAEGLIGSGGKIDAAFLALAPNLRAASTISVGYDNFDVDALSARGIVLMHTPTVLTETVADTMMALMLATARRVVELAERVKAGEWTESIGDDWFGVDVHGKTIGILGMGRIGMALAQRAHFGFGMPVLYTDTRPHPEAEARFGARHCSLDTLLAEADFLCITLPMTPETHHMIGAEQLAKMKPSAILINAGRGPVVDEQALIAALQDGTIHAAGLDVFEQEPLPVDSPLLTLKNVVALPHIGSATHETRYNMAACAVDNLIAALTGKVKENCVNPQVLATH

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	94.7
NLMSIM	85.0
AACOMP	92.5
Seqdif (SeqID)	11.0 (WP_050093702.1)
Structdif (F-Target)	5.8 (2dbq A)

ProtNLM

Name	Score
Glyoxylate/hydroxypyruvate reductase B	0.383
1.1.1.79	0.380
1.1.1.81	0.210
Gluconate 2-dehydrogenase	0.005
D-glycerate dehydrogenase	0.004
Bifunctional glyoxylate/hydroxypyruvate reductase B	0.002