M2DU0

Prompt

1.6.5.9

Oxidoreductases. Acting on NADH or NADPH. With a quinone or similar compound as acceptor. NADH:ubiquinone reductase (non-electrogenic).

AI Generated Sequence

462 AAs

MLKIIIPTIMLFPTTWLSKPKWIWTNTTAHSLLIALISLTWLKQTSENGWTSSNLYLATDPLSTPLLVLTCWLLPLMILASQNHISPEPLTRQRLFITLLASLQLFLIMAFGATEIIMFYIMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTLAGSLPLLVALLLLQNSMGTLSMLVLQYSQPLQLSTWGDKIWWAGCLIAFLVKMPLYGVHLWLPKAHVEAPVAGSMVLAAVLLKLGGYGMMRMTVLLDPLTKEMAYPFIVLALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAAGILIQTPWGFAGAIILMIAHGLVSSMLFCLANTAYERTHSRTMILARGLQMIFPLMAAWWFIASLANLALPPLPNLMGELMIITALFNWSPLTILLTGVGTLITAGYSLYMFLMTQRGPTPSHITGLTPSHHREHLLMALHLLPLLLLTLKPELIWGWELSA

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	94.0
NLMSIM	75.0
AACOMP	85.7
Seqdif (SeqID)	10.9 (YP_009349082.1)
Structdif (F-Target)	2.0 (7v2c r)

ProtNLM

Name	Score
NADH-ubiquinone oxidoreductase chain 4	0.540
7.1.1.2	0.453
NADH dehydrogenase subunit 4	0.006
NAD(P)H-quinone oxidoreductase chain 4	0.000
NDH-1 subunit M	0.000
1.6.5.3	0.000