MREGP

Prompt

This protein is part of the ABC transporter superfamily and functions as an ABC-type amino acid transporter. It facilitates the movement of amino acids across cellular membranes.

AI Generated Sequence

241 AAs | 26.84 kDa | 28.66 kDa (with tag)

MIEIKNLSKSYGDFHVLKGINLTIKKGEVVCVIGPSGSGKSTLIRCINGLEEIQSGEIIIDGKDITDPKTNINKLRSEVGMVFQHFELFPHLTVLENVTLAQIKVLKRDKAEAEKKALELLERVGLAEHADKYPAQLSGGQQQRVAIARALAMDPIAMLFDEPTSALDPEMINEVLDVMVELAKEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDDKPEEFFGNPKSERTKLFLSKILH

Ligand/Cofactor

Adenosine triphosphate

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Computational Metrics

PLDDT

GPT Score

82.79

AAComp

91.7

DiffDock Confidence

-1.06

Seqdif (SeqID)

76.76 (WP_271269145)

Structdif (F-Target)

98.12 (4yms A)

ProtNLM

Name	Score
Amino acid ABC transporter ATP-binding protein	0.292
Glutamine transport ATP-binding protein GlnQ	0.087
ABC transporter, ATP-binding protein	0.050
ABC transporter domain-containing protein	0.045
Arginine transport ATP-binding protein ArtM	0.044
Peptide ABC transporter ATP-binding protein	0.041
Glutamine ABC transporter ATP-binding protein	0.036
Polar amino acid transport system ATP-binding ...	0.035
Arginine ABC transporter ATP-binding protein	0.030
Arginine ABC transporter, ATP-binding protein ...	0.025

Experimental Results

Company	Variant	Expression System	Concentration (mg/ml)	Total Yield (µg)	Purity (%)	TM (°C)	Tm(oC w/2mM AMP-PNP)
Tierra	T3	Enzyme Optimized System	0.9 (Lunatic)	45	100	N/A	N/A
Tierra	T4	Enzyme Optimized System	0.94 (Lunatic)	47	100	N/A	N/A
Tierra	T3	Biologics Optimized System	N/A	N/A	N/A	N/A	N/A
Tierra	T4	Biologics Optimized System	N/A	N/A	N/A	N/A	N/A
Arctoris	N/A	E. coli	N/A	N/A	N/A	N/A	N/A

Data

12atp_-1.00 | 15