MB6BK

Prompt

This protein is involved in telomere maintenance and binds to heterocyclic compounds.

AI Generated Sequence

280 AAs | 31.63 kDa | 33.45 kDa (with tag)

MSEEELQRALDFINTGESIFLTGGAGTGKTTLINILNEITKKKKVVVLAATGVAAINVGGQTIHSFFGIPLGPVQDDDIDEENKRRSLKRLINTIETIVIDEISMVRADILDAVDRVLRQVRNRREPFGGVQVLLFGDFQQLPPVIKSDEERDIFDQFKRSPYFFDAKVWKELELVEIELTKVRQQDDVKFIDLLNHVRLNQVTEEHLQALNERYGADIRPEEIDAITLAHTRNMVDSINEAKLAKLPGEPVEIKGEIEGDFEKRGPTPEQELKLKIGAQ

Ligand/Cofactor

Adenosine triphosphate

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Computational Metrics

PLDDT

GPT Score

49.27

AAComp

91.22

DiffDock Confidence

-1.31

Seqdif (SeqID)

51.56 (KAA5211474)

Structdif (F-Target)

87.28 (5fhd B)

ProtNLM

Name	Score
AAA family ATPase	0.342
Helicase	0.340
ATP-dependent DNA helicase	0.080
AAA domain-containing protein	0.060
ATP-dependent RecD-like DNA helicase	0.048
3.6.4.12	0.020
PIF1-like helicase	0.018
ATPase	0.017
AAA ATPase	0.009
PIF1 helicase	0.003

Experimental Results

Company	Variant	Expression System	Concentration (mg/ml)	Total Yield (µg)	Purity (%)	TM (°C)	Tm(oC w/2mM AMP-PNP)
Tierra	T3	Enzyme Optimized System	0.23 (Lunatic)	11.5	100	N/A	N/A
Tierra	T4	Enzyme Optimized System	0.24 (Lunatic)	12	100	N/A	N/A
Tierra	T3	Biologics Optimized System	0.01 (Lunatic)	0.5	100	N/A	N/A
Tierra	T4	Biologics Optimized System	0.21 (Lunatic)	10.5	100	N/A	N/A
Arctoris	N/A	E. coli	N/A	N/A	N/A	N/A	N/A

Data

55_-1.17t | 49