M2RXT

Prompt

This protein is involved in cholesterol and lipid metabolism and helps in transporting lipoproteins.

AI Generated Sequence

228 AAs | 25.16 kDa | 26.98 kDa (with tag)

MSDAPVLELRDLTKTYQQGEGEVTVLRGVDLSVAPGEMVAIVGASGSGKSTLLHIAGLLDRPTSGEVWLGGEDHTRLSEAERTRFRNETIGFVYQFHHLLPEFTALENVMLPQLIRGVGAAEARARALELLERLGLGHRADHRPAELSGGEQQRVAIARALVNRPRLLLADEPTGNLDPRTAEQVLDLLFELNRELGLTAVVVTHDLELARRMDRVLRLRDGRLVELE

Ligand/Cofactor

Adenosine triphosphate

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Computational Metrics

PLDDT

GPT Score

61.68

AAComp

88.17

DiffDock Confidence

-1.19

Seqdif (SeqID)

65.49 (MDG1118236)

Structdif (F-Target)

94.56 (2pcj B)

ProtNLM

Name	Score
Lipoprotein-releasing system ATP-binding prote...	0.581
7.6.2.-	0.413
ABC transporter ATP-binding protein	0.001
ATP-binding cassette domain-containing protein	0.001
3.6.3.-	0.001
Macrolide export ATP-binding/permease protein ...	0.000
Lipoprotein-releasing ABC transporter ATP-bind...	0.000
Lipoprotein-releasing system ATP-binding prote...	0.000
Lipoprotein releasing system ATP-binding prote...	0.000
Lipoprotein-releasing system ATP-binding prote...	0.000

Experimental Results

Company	Variant	Expression System	Concentration (mg/ml)	Total Yield (µg)	Purity (%)	TM (°C)	Tm(oC w/2mM AMP-PNP)
Tierra	T3	Enzyme Optimized System	0.53 (Lunatic)	26.5	97.7	N/A	N/A
Tierra	T4	Enzyme Optimized System	0.77 (Lunatic)	38.5	87.5	N/A	N/A
Tierra	T3	Biologics Optimized System	0.27 (Lunatic)	13.5	62.7	N/A	N/A
Tierra	T4	Biologics Optimized System	0.19 (Lunatic)	9.5	100	N/A	N/A
Arctoris	N/A	E. coli	N/A	N/A	N/A	low confidence	low confidence

Data

57atp_-1.29t | 21