MZSR6

Prompt

1.1.1.174

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. cyclohexane-1,2-diol dehydrogenase.

AI Generated Sequence

735 AAs

MKKILIIGLGLIGGSLALDIKKKYPDIEIIGYGNNEKTLEIALELGIIDEITLDLKKAAEKADFIILAVPVGATIEFLKKLADLDLKEGVIISDTGSTKAAIVKAAEEYAPKGVNFIGGHPMAGSHKTGPEAAKADLFENAYYIITPEELTAPEVLELVKKLIKGTGAHIIEMDPKKHDEVTAQISHLPHIIAFGLVNQVAKFEEDLEHIFRLAAGGFRDMTRIASSDPAMWTSIFLSNKEHILEVLDRFKKQLDEIKEAIEAGDGEAIYNMFTQAKEHRDQIEKIHKRAAVPAFDLFINVPDKPGAILEVAGYLAGKRIVNLKHVGVSNREDIEHGLREITLFKAGLEEAAEKLTQLNDMGMTVVETNHHNGVFIHTVGLKGLKLPKEELYLNKSGTSTLRLVDGLLSLVDVDSVLTGDALSKRNIERVIKSLKENGAKILNTAEGRTPINFMGGTKKLGKIYEMPADRKLVESALLLAALYEEKTEIVTEPETRHMIDTLLNAIGGHEIVEGEKITLLSGGKKILVAKDIEESDISSAAFLFMVAAIKEGADILLNEVGVNPTREGVIEILQLMGADIEVKNERIVGGEKIADIHVVRAALKGIKYDEEQVLLAIDEFPTLFIAAVCAEGNTVIRTAEELRVKESRIQLVMDGLTKHIGIDCIPTEDTIIIEGKPGIQGKTIESHGDERIAMSFSVGSLNRTENIRIHDCENVAEKFENFLWLYDKLGIRIVA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	77.1
NLMSIM	60.0
AACOMP	90.6
Seqdif (SeqID)	52.8 (WP_231982510.1)
Structdif (F-Target)	5.4 (4wji 2)

ProtNLM

Name	Score
1.3.1.12	0.564
Prephenate dehydrogenase	0.250
1.3.1.43	0.023
Arogenate dehydrogenase	0.015
3-phosphoshikimate 1-carboxyvinyltransferase	0.013
EPSP synthase	0.011