M2HI8

Prompt

6.3.5.13

Ligases. Forming carbon-nitrogen bonds. Carbon--nitrogen ligases.with glutamine as amido-N-donor. lipid II isoglutaminyl synthase (glutamine-hydrolyzing).

AI Generated Sequence

297 AAs

MSRLTLATIAGRAARWLSRLARRGGSALPGRVALQLDPRLLAALARRHDVVVVTGTNGKTTTANLIARALREAGFRVLTNPTGANMPAGITAAFLARARGAGRPVAVLEVDEAHLPRVAREIRPELVVLTNLFRDQLDRYGEIVTLTRRIREGARRAPAAVVLNADDPLLFSAARLPAPVVWYGGVDWAADDAARPCTDGVLCPRCGRPLRYRGEVYAPLGPRWCPACGFRRPPDYRWTVDDLALPGHRRLRVDGQVAYEIPPGVNNVYNALAAVAAVARFLGVPPEAIRALERYRV

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	87.1
NLMSIM	70.0
AACOMP	85.6
Seqdif (SeqID)	52.9 (WP_301058502.1)
Structdif (F-Target)	23.4 (7q8e C)

ProtNLM

Name	Score
DUF1727 domain-containing protein	0.613
6.3.5.13	0.093
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT	0.092
Mur ligase middle domain protein	0.052
Mur_ligase_M domain-containing protein	0.026
Mur ligase family protein	0.016