MYXHP

Prompt

1.2.1.36

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. retinal dehydrogenase.

AI Generated Sequence

499 AAs

MATLPALKKYKVLKNGHFIPGWGLGPWQSPKGEVVKPAVKEAIDAGYRHFDCAHVYQNEAEVGQAIQAWKKGAVPKREELFIYSKLWGTFHRADLVRASLEKTGLKLQLDYVDLYLIHWPFAFKAGDALLPVDEGKTIIPETDFTLATWEAMEGCVAGLWPKNIGISFFNWKLAPAIIACGATVVKPANVQVECHPYLVQKLIEQGFPKAGVINVVYGPLGATGAPWSVHPDVKVLLFDGSTAGAIAKKYKTAAKLVKRTLELGGNSPIIVKSDAPDIEENIQVFDFLFNTSGMCTLALSRNQHIVYIDELVTRMKEYVEFAEKFGDPFEPKTNMGAQINKKHLDKVLGFIKIGQEHGAKLLCGGEHVDGKGYFIQPTVFTDVNDDMRIAKEEIFGPVLAILPFKTVEEAIELANSTDYGLAAGVFTQDLNRAHRVIADLEYGRVWINCYNLVAPEQPFGGYKMSGFGRELGKYGLRDYTKPLTVHMKLPNKNWEWFKV

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	70.8
NLMSIM	75.0
AACOMP	92.8
Seqdif (SeqID)	60.7 (HTB12231.1)
Structdif (F-Target)	37.6 (3efv A)

ProtNLM

Name	Score
Aldehyde dehydrogenase	0.376
Aldehyde dehydrogenase family protein	0.082
Aldehyde dehydrogenase, mitochondrial	0.072
Aldehyde dehydrogenase (NAD+)	0.066
Betaine-aldehyde dehydrogenase	0.056
Aldedh domain-containing protein	0.056