MVD6W

Prompt

6.5.1.5

Ligases. Forming phosphoric ester bonds. Forming phosphoric ester bonds. RNA 3'-terminal-phosphate cyclase (GTP).

AI Generated Sequence

433 AAs
MKKIKILGFKGGGSFIRQALALSLLTGKPIYIENIRAGDPNPGLKPHELSLLRLLAELTGAEVEGLEYTGTTLYFKPGLIKGGKYHFDCGMTAGISYLLQPLLLALPFAKGPVKVTLKGGTVNDVKFSVDYFRETVLPILEKMGIEGVELKIKRRGFIPKGGGEVEFVFGPVLKLPNLTLEEKGTIKRIRGIAHSTLNVSHIAERMIDASREILNKFDLPVDIYTDRQYGKPGSGIHVWPEIGILAETTNLLGFRSEAESVGKEAAEKVIEDLGKGCAVDEMLEDQILPLVALAHQSKLTTLTEMTLHLTRNIAVIEGFVTAYFIEKLNGLKGFKVGKGWGIRDEGTENMDKVLFIKGVEGTGLVNIGKILGGGLKIPVKIKGKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Ligand/Cofactor

GTP

C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N

Validation Metrics

PLDDT76.5
NLMSIM85.0
AACOMP82.8
Seqdif (SeqID)60.7 (RLG85651.1)
Structdif (F-Target)5.9 (4o8j B)

ProtNLM

NameScore
RNA 3'-terminal phosphate cyclase0.325
6.5.1.40.203
RNA-3'-phosphate cyclase0.088
4.2.3.50.075
3-phosphoshikimate 1-carboxyvinyltransferase0.063
5-enolpyruvylshikimate-3-phosphate phospholyase0.039
Designed by MP, using an AMD MI250 GPU