MWPNT

Prompt

6.3.4.18

Ligases. Forming carbon-nitrogen bonds. Other carbon--nitrogen ligases. 5-(carboxyamino)imidazole ribonucleotide synthase.

AI Generated Sequence

358 AAs

MTTPLPPGATIGILGGGQLGRMLAAAAARMGYRTHIYAPDPDCPAAQVAHRHTAAPYDDPAALAALAEACDVVTYEFENVPAAALAELAARVPVRPSARALEVSQDRLTEKAFLADLGIPTAPFAAVADAAALDAALADLGAPAILKTRRFGYDGKGQARLAAPADAAAAWAALGGAPAILEGFVPFAREVSVIAARGADGAVACYDPAENVHRDGILRTTTAPARIGPATAAAAEALARRILAALDYVGVLGVELFVTPDGALVANEIAPRVHNSGHWTIEGCAVSQFEQHIRAVCGWPLGDGARHADAVMENLIGDLDAVAPWAALLALPGAALHLYGKAEARPGRKMGHVTRLAA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	95.3
NLMSIM	90.0
AACOMP	82.9
Seqdif (SeqID)	28.0 (MCA8882577.1)
Structdif (F-Target)	3.5 (3qff B)

ProtNLM

Name	Score
6.3.4.18	0.265
N5-CAIR synthase	0.253
N5-carboxyaminoimidazole ribonucleotide synthase	0.242
5-(carboxyamino)imidazole ribonucleotide synthetase	0.232
5.4.99.18	0.001
5-(Carboxyamino)imidazole ribonucleotide synthase	0.000