MT7T2

Prompt

1.1.1.150

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 21-hydroxysteroid dehydrogenase (NAD(+)).

AI Generated Sequence

500 AAs

MKVLVTGGCGFLGRHIVEMLVEEGHLEVRALDRVFRPELKEAGVTVLQGDITDEASVRAACDGIDVVFHTASIVDVWGIPHRTISRVNVKGTQNLLDACVASGVKALVYTSSASVAGPNYTDLINGDESLPYATKWMDAYSETKAIAEKLVLAANGDTLYTCALRPAGIYGERDPQLLPRIVEVARNGKLKFQIGDNKNLVNFTYVENVAWAHILAARDLADPAAKPVAGQAYFINDGEPVYSYDFLNRLLEEWGYERDPRMTLPLALAYLFAFLLEVVWFLLRPIGFEPPLFTRHTVALTCTTFFYSCEKARRDLGYAPVVSLEEGIKRTVEWVGHMVEKRGKDLKADLWGRVIDTILWGDTKRGTLTLVTDPATYINQEHPVTVLLAATYVFDFSVGETYTIAAPFVLLLAEAGYVHLLGSPNTFYGTKLKRLHFAGHRFTDEKGKRVSDVTVGNVAWAHILAADRLLDPAAGKPVQGQAYFITDGTPHMSWDFLNRV

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	76.1
NLMSIM	85.0
AACOMP	94.2
Seqdif (SeqID)	50.7 (XP_032737202.1)
Structdif (F-Target)	11.4 (3aw9 2)

ProtNLM

Name	Score
3Beta_HSD domain-containing protein	0.620
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0.064
NAD-dependent epimerase/dehydratase family protein	0.036
NAD(P)-dependent oxidoreductase	0.028
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	0.020
Sterol-4alpha-carboxylate 3-dehydrogenase (Decarboxylating)	0.019