MPXCG

Prompt

4.2.1.47

Lyases. Carbon-oxygen lyases. Hydro-lyases. GDP-mannose 4,6-dehydratase.

AI Generated Sequence

432 AAs

MTKRALITGITGQDGAYLAELLLEKGYEVHGIKRRSSLFNTQRIDHLYQDPHEHNVRFRLHYGDLTDSSNLIRIIQEVQPDEIYNLGAQSHVAVSFEEPEYTANADAIGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEVPQKETTPFYPRSPYAVAKMYAYWITVNYREAYGMFACNGILFNHESPLRGETFVTRKITRAVANIALGLQDCLYLGNLDALRDWGHAKDYVRMQWLMLQQDEPEDFVIATGVQYSVREFVRMSAAEVGIELRWEGQGVDEVGIVDSVTGKPAYDLKVGDVVVRVDPRYFRPAEVETLLGDPSKAREKLGWVPEISFQEMVKEMVASDLEMARRDHLLKAHGYDLALNLESPAERNHSEERRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRR

Ligand/Cofactor

GDP-mannose

C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OC4C(C(C(C(O4)CO)O)O)O)O)O)N=C(NC2=O)N

Validation Metrics

PLDDT	90.2
NLMSIM	70.0
AACOMP	87.2
Seqdif (SeqID)	18.2 (MBB1201499.1)
Structdif (F-Target)	3.9 (7kf3 B)

ProtNLM

Name	Score
GDP-D-mannose dehydratase	0.402
GDP-mannose 4,6-dehydratase	0.312
4.2.1.47	0.280
GDP-glucan 4,6-dehydratase	0.000
NAD(P)-bd_dom domain-containing protein	0.000
NAD-dependent epimerase/dehydratase family protein	0.000