MP493

Prompt

2.5.1.83

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific].

AI Generated Sequence

401 AAs

MAKLTTRERFNAVFPVLVEDILADAKAYGLPEEALRWYKQSLNYNVLGGKCNRGMSVPDTVSLLLGKPLTDEEYFKAATLGWCMEWLQAFFLVSDDIMDSSITRRGQPCWYRLEGVGMIAINDAFMLEAAIYTLLKKHFRSHPAYVDLIELFHEVTFQTELGQLCDLLTAPEDKVDLDKFSMEKYTFIVIYKTAYYSFYLPVALAMYQMGLATPENLKQAEDILIPLGEYFQIQDDYLDCFGLPEHIGKIGTDIKDNKCSWLVNQALARATPEQRKILEENYGRKDPAHEAKVKKLYDELKLEQVYREYEEKFVGELNAMIAAIDDSEGLKKEVFLAFLAKIYKRTKDKFQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FPP

CC(=CCCC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C)C

Validation Metrics

PLDDT	92.9
NLMSIM	60.0
AACOMP	87.3
Seqdif (SeqID)	18.2 (XP_053012749.1)
Structdif (F-Target)	3.0 (7bux A)

ProtNLM

Name	Score
Farnesyl pyrophosphate synthase,	0.286
Farnesyl pyrophosphate synthetase,	0.168
Farnesyl pyrophosphate synthase	0.132
Farnesyl diphosphate synthase	0.045
Farnesyl pyrophosphate synthase 1,	0.043
2.5.1.10	0.042