MPCAI

Prompt

3.7.1.22

Hydrolases. Acting on carbon-carbon bonds. In ketonic substances. 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing).

AI Generated Sequence

619 AAs

MTTIRLTTAQALVKFLDAQYVEVDGKKVPFVKGIFTIFGHGNVLGIGEALEQAGDHLKVYQGRNEQGMAHAAIAFSKQKLRKQIMACTSSIGPGAANMVTAAATAHVNRIPVLLLPGDVFATRQPDPVLQQIEQFHLGTISTNDAFRPVSKYWDRITRPEQLMTAAPRAMRVLTDPAETPGATLCLCQDVQGEAWDYPESFFEKRVHRIDRRLPDAAMLADAVALIRAAKKPLIIVGGGVRYSGAEAALKAFAEAHGIPFAETQAGKGSLESDHPLNVGGIGVTGSLAANLIAREADLVIGVGTRYTDFTTGSKWLFQNPEVEFITLNVGMFDAHKLDALPVVADARETLAALAAGLGGWQVASGWTDEIAALKAAWLAETERLYALALGTCLTQAGVLGAINRHVDPDAIVLCASGTLPGDLHKLWRTRKPNTYHVEYGYSCMGYEINAALGVKMAEPDREVYVMVGDGSYLMLHSELVTSVQEHKKITVLLLDNSGFGCINSLQMANGGSGFGNEFRYRPETGKLDGGLIPVDFAANAESYGCKTYRVNTVAQLEAALADARAQTVSTLIDIKVLPKTMTNGYESWWDVGVAEVSQRPATRAAYAALVANLQQARGY

Validation Metrics

PLDDT	85.1
NLMSIM	90.0
AACOMP	94.3
Seqdif (SeqID)	34.0 (WP_078408940.1)
Structdif (F-Target)	5.8 (6lpi B)

ProtNLM

Name	Score
3.7.1.22	0.327
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (Decyclizing)	0.302
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	0.152
3.7.1.-	0.026
Malonic semialdehyde oxidative decarboxylase	0.025
Thiamine pyrophosphate protein central region	0.024