ML9CB

Prompt

1.1.1.27

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. L-lactate dehydrogenase.

AI Generated Sequence

310 AAs
MKIGIIGAGRVGASTAYALLQRGLADELVLIDVDRDRARGEAMDLQHGLPFAGRMRIWAGDYADCAGADVVVITAGVAQKPGETRLDLVGRNVAIFKGIVPQVMAHSPDAILLVASNPVDVMTYVAWKLSGLPRHRVIGSGTVLDTARFRYLIGEHLGVAPRSVHAYILGEHGDSEVPAWSGANVAGVPLRELCAQRGERCDAEWLAEIHEQVRNAAYEIIEGKGATYYGIAMALARIVRAILRDEHAVLTVSSLLDGEYGVHDVCLSVPAVVGRAGVERVLELPLSDAERAALAHSAETLRAVADELAL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT91.9
NLMSIM90.0
AACOMP90.1
Seqdif (SeqID)34.0 (MBC7250238.1)
Structdif (F-Target)3.0 (4a73 D)

ProtNLM

NameScore
L-lactate dehydrogenase0.423
1.1.1.270.332
L-LDH0.238
LDH0.001
L-lactate dehydrogenase 20.000
Lactate dehydrogenase0.000
Designed by MP, using an AMD MI250 GPU