MOJOB

Prompt

1.1.1.279

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. (R)-3-hydroxyacid-ester dehydrogenase.

AI Generated Sequence

315 AAs

MKILVTDAIDLKTHGLNALKLGFEVIDYFDYTPQQPEIIARAKDAEGIILNKVVIDRKVLAQAPKLKLICITATGTDNIDVAAAKAHGIEVKNTVAYSTESVAQHVLALILSLLRNLNDYNRDLKTGKWTQKDAFALHPFLMLGDLYGKKWGIIGLGNIGRKVAKIAKAFGMEVLYYSKKPKEAEGYEYVELEELLKTSDIISLHAPLNEQTKHLIGAEELKLMKEGAILINTGRGGVVNEQALAEALKNKELYYAYDVYEKEPLFKNHPLLKLKNVLITPHIAWASLESYKKIVDLALKNIEAFLKGEKPNLVN

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	85.7
NLMSIM	60.0
AACOMP	89.3
Seqdif (SeqID)	42.8 (WQT20732.1)
Structdif (F-Target)	5.8 (6p2i B)

ProtNLM

Name	Score
Hydroxyacid dehydrogenase	0.255
D-2-hydroxyacid dehydrogenase	0.198
1.1.1.29	0.193
Glycerate dehydrogenase	0.123
2-hydroxyacid dehydrogenase	0.039
D-3-phosphoglycerate dehydrogenase	0.038