MNKS4

Prompt

2.5.1.56

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. N-acetylneuraminate synthase.

AI Generated Sequence

388 AAs

MRRVVIIAEIGVNHNGDLDLALELIDAAAEAGADAVKFQTYRPETMTVPERERDFRIQGSLWGDRTYQELYRRHELTLEEHEALRRYCRELGIDFLSTPFDEASVDFLEDLDVPAYKIASGELTNHPLLRRVAATGKPVILSTGMATMEEIEEAVRTLREAGCNDVVLLHCTSTYPTPVEDVNLRAMGTLAERFGVPVGYSDHTEGLQVSIAAVALGARVFEKHFTLDRTMPGPDHRASLEPEELRAMVRDIRTIEMALGDSEKKPTEREVARNRLARRSLVAVRDIRAGEVFTEDNLAVRRPGTGLAPRHWHDVIGRRATRDIAAGETIEWDVVDPRAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

PLP

CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O

Validation Metrics

PLDDT	95.2
NLMSIM	85.0
AACOMP	85.2
Seqdif (SeqID)	42.8 (WP_011392277.1)
Structdif (F-Target)	9.2 (8h2c C)

ProtNLM

Name	Score
N-acetylneuraminate synthase	0.543
2.5.1.56	0.170
AFP-like domain-containing protein	0.041
N-acetylneuraminic acid synthase domain-containing protein	0.029
2.5.1.101	0.028
N-acetylneuraminic acid synthetase	0.021