MNW7U

Prompt

1.21.3.1

Oxidoreductases. Catalyzing the reaction X-H + Y-H = 'X-Y'. With oxygen as acceptor. isopenicillin-N synthase.

AI Generated Sequence

360 AAs

MATPVIDLSLLDGDPARRAVAERVGDACREWGFFYVTNHGVDHALLDRVRAAFAAFRALPEAEKAAIAARGDPARGYNTYGRELYAGKVDWRESLYFLNPADLADHPRLAAHPAANVWPDDWPAFRAFTEAWYARDLALAADLFRLLAEALGLRERFFAAACDDAGDLLKLVNYYPPCPEPALARLGEHTDMGGITLLFQEQVPGLQVLRDGGWIDVAPLPGALVVNCGDLLQWLTNGRYRSAPHRVTVWPGRERLSLPVFFNLPPDTVVAPLPELAADGAPPPPPVTYAEYLRGYLKTKLKQGKPGLLRAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	85.0
NLMSIM	60.0
AACOMP	80.4
Seqdif (SeqID)	56.6 (TVS00865.1)
Structdif (F-Target)	10.5 (3oox B)

ProtNLM

Name	Score
Fe2OG dioxygenase domain-containing protein	0.498
Isopenicillin N synthase	0.030
2-oxoglutarate-dependent dioxygenase	0.023
Oxidoreductase	0.019
Isopenicillin N synthase-like	0.012
1.14.20.6	0.011