ME026

Prompt

5.1.99.6

Isomerases. Racemases and epimerases. Acting on other compounds. NAD(P)H-hydrate epimerase.

AI Generated Sequence

500 AAs

MKPVLTVEQIRALDRNAIEKLGLPGLLMERAAGVVANAAFGHLPEVGRHVLVAGCGNNGGDGLAVARLLAAGHRPVTVLLVGRPEGLPELARANLAAVVNGVPVWQALGEAGLAGADLLVDALFGTGLRGPLPEPFAALVARANALGLPVLAVDVPSGLHADTGEPGGPAVRAQHTVTFHLLKPGLLPGRRAACGTVELLPIGFPWDLVREPGILYGGLPAGLLPLRPVMSHKGRGFVLKVVAGAATGYGAARLTAARAARTAGLVTVGYADGVRHALASRAPVLVLGRVPGGRGVCMDLIVDVDTVCVGPGFGTDETLLGQALALAPADWAEAVLDGDALTALGRPGRLRRLHGGPVLTPHAGEFARLLGCTRAEVAHRIEAARRLAARYGGVVLLKGPHTVIAAPDGRAYVNATGNPGLAAGGSGDVLTGIIGGLLAQGMAPFDAACAGVWLHGLAGRLAAERHGPRGLMAADLLPHLPRVWRGLGEGGGGGGGGGGG

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	82.9
NLMSIM	70.0
AACOMP	83.9
Seqdif (SeqID)	56.6 (WP_066665952.1)
Structdif (F-Target)	10.0 (3rss A)

ProtNLM

Name	Score
ADP-dependent NAD(P)HX dehydratase	0.257
5.1.99.6	0.138
Nicotinamide nucleotide repair protein	0.133
NAD(P)H-hydrate epimerase	0.129
Bifunctional NAD(P)H-hydrate repair enzyme	0.122
ADP-dependent (S)-NAD(P)H-hydrate dehydratase	0.113