MIO2Y

Prompt

4.2.1.68

Lyases. Carbon-oxygen lyases. Hydro-lyases. L-fuconate dehydratase.

AI Generated Sequence

435 AAs
MTTITSLRVHDIRFPTSLSLDGSDAMNPDPDYSAAYVILETDGPGLKGHGLTFTIGRGNEICCAAIEAMRHLVVGRDLDWICADPGRFWRHLTSDSQLRWIGPEKGAMHLATGAIVNAVWDLWAKAEGKPVWRLVADMSPEQLVDCIDFRYLTDAITPEEALDILRRAEPGKAERIAILEKEGYPCYTTSAGWLGYSDDKLRRLCQEAVDAGFNHIKMKVGRDLDDDIRRITIAREVIGPDRYLMIDANQVWEVGQAIDWVRKLAFAKPWFIEEPTSPDDVLGHRKIRQAIGPVKVATGEMCQNRIVFKQFIAEGAIDVVQIDSCRMGGLNEVLAVYLMAAKFGLPVCPHAGGVGLCEYVQHLSMIDYIAVSGTKEGRVIEYVDHLHEHFVDPCVIRDAAYMPPQAPGFSIEMKPESIAQYTFPDGPRWRDWAEK

Ligand/Cofactor

L-fuconate

CC(C(C(C(C(=O)[O-])O)O)O)O

Validation Metrics

PLDDT85.4
NLMSIM90.0
AACOMP93.6
Seqdif (SeqID)15.2 (WP_157018114.1)
Structdif (F-Target)3.1 (1yey C)

ProtNLM

NameScore
L-fuconate dehydratase0.519
4.2.1.680.473
Fuconate dehydratase0.002
Dihydroxy-acid dehydratase0.000
RhamD0.000
5.1.3.320.000
Designed by MP, using an AMD MI250 GPU