MIO2A

Prompt

1.12.5.1

Oxidoreductases. Acting on hydrogen as donors. With a quinone or similar compound as acceptor. hydrogen:quinone oxidoreductase.

AI Generated Sequence

293 AAs
MHKQGITRRDFMKFCGAVTASLGLGPSFAPKVAEALETKNRPVVWLHAMECTGCSESFIRSAHPTLDAVIFDNISLDYHETLMAAAGWQAEEALHEAMKKYKGNYILMVEGAIPLGENGMYCITGGKPFSELVHKAALNAKAIIAIGSCTSCGGVQAAYPNNPGAQGVSKVITDKPIVNVPGCPPNPENMTGVILYLITFGRLPELDRMNRPKWMYGQKIHDTCERRGHFDAGQFVQEFGDENAKDGYCLYKVGCKGPYTYNACPKVRFNGVTSWPIGAGHGCIGCTEKDFWD

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT87.7
NLMSIM80.0
AACOMP92.0
Seqdif (SeqID)34.4 (WP_144570392.1)
Structdif (F-Target)5.6 (4c3o D)

ProtNLM

NameScore
1.12.2.10.164
Ni/Fe hydrogenase0.160
1.12.99.60.120
Hydrogenase small subunit0.092
Hydrogenase (NiFe) small subunit HydA0.073
Twin-arginine translocation signal domain-containing protein0.057
Designed by MP, using an AMD MI250 GPU