MFPLJ

Prompt

1.1.1.143

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. sequoyitol dehydrogenase.

AI Generated Sequence

394 AAs

MKALVLEKPGEIRLREVDLPEPAGPGDVLIKVRTVGVCGSDVHYYTHGAIGPFVVEAPMVLGHEAAGTVVAVGAGVTGLKVGDRVCMEPGIPDPASAASRLGRYNLCPDVRFWATPPVHGALTPYVTHPAAFTYRLPDNVSFEEGAMVEPFSVGMQAAQRARVTPGDTALVTGAGPIGMMTALAALAAGCARVVVTDIAAGKLAIARELGAVETINVRRETPAQAIAELTDGWGADVAFEASGAPAAMATLYPAVRPGGTVVQVGMPVDPVPVDIAAAQAREVRIETVFRYANIYPRAIALLASGRLDLRPLVTGTFALDDSVAAFAAAAAPGADPVKLQIVPAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	90.6
NLMSIM	70.0
AACOMP	82.4
Seqdif (SeqID)	33.1 (WP_183993023.1)
Structdif (F-Target)	4.4 (3qe3 A)

ProtNLM

Name	Score
NAD(P)-dependent alcohol dehydrogenase	0.312
D-xylulose reductase	0.191
1.1.1.9	0.133
Sulfurtransferase	0.131
Alcohol dehydrogenase catalytic domain-containing protein	0.102
L-iditol 2-dehydrogenase	0.014