MF10R

Prompt

1.2.1.48

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. long-chain-aldehyde dehydrogenase.

AI Generated Sequence

499 AAs

MSLLDLLDQLKQLPLLDLPLLFINGEWVDSVSGKTFETINPATGEVIGQVAEGSKEDVDKAVAAARKAFQGPWAKTTPRERGRILLKIADLIEQNKDLLAAIESLDNGKPLREALGDVDLACDHFRWYAGWADKLEGKTIPSIDPNTLSYTHQEPVGVVGQIIPWNFPLLMAAWKIGPALACGNCVVLKPAEQTPLSALLLCELIKDAGLPPGVVNIVNGLGREAGEALASHPMIDKIAFTGSTTVGKLIMKYAAENLIPVTLELGGKSPFIVFEDADLDQAVEGAAFGIFYNHGQVCTAGSRLYVQESIYDKFIEKFVERTKKIKVGDPLDENTQIGQLVSKEQFDKILSYIDIGKKEGAKLLTGGKRLGEKGYYIEPTVFTDVKNDMKIAQEEIFGPVLSVTKFKTVEEVIKRANDTEYGLGAGVFTRNINRALRVARALEAGVVWVNCYHLADASVPFGGYKQSGNGRELGKYGLDHYTQVKTLVINLGGKNPGYL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.1
NLMSIM	70.0
AACOMP	93.9
Seqdif (SeqID)	36.9 (HEV8072285.1)
Structdif (F-Target)	2.0 (4qf6 C)

ProtNLM

Name	Score
Aldehyde dehydrogenase	0.296
Betaine-aldehyde dehydrogenase	0.285
Aldehyde dehydrogenase family protein	0.132
1.2.1.3	0.060
1.2.1.8	0.024
Aldehyde dehydrogenase (NAD+)	0.024