MD96E

Prompt

1.1.1.58

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. tagaturonate reductase.

AI Generated Sequence

499 AAs

MTQLTALNRAVIQPTYDRHQLVERIVHLGFGAFFRAHEQVLYTHLMNEHDLSGWGICEVNLPGDEQQIQDLQKDQLCTYVAELGKDAWQTAVVRKISEALHANIDGLEAVLAKMAEPQIAIVSMTVTEKGYHCHPATGELDLNHLIQHDLQHPQEHPKTAVGFIVAALARREKAGLPGFTLMSDCNMRENGEVVRAVVIALAEAIGTPLADAWIANVSFPATMVDTIVPAVTEEALAKIEALTGVTDPCAIAEYPRFVQWVIEDNVNGRPDWDKAGVQLVSDVLPYEEMKLRMLNGSHSALAYLGYLAGLEHITDAMQDEAIYRYARALMFEEQAPTLSVEGVDLDAYADSLIERFSNPALKHRLWQIAYDGSQKLPQRILDSIRLHLENGTPCRFLAFGVAAWMRYVGGVDENGEPIEVRDPLLAEIQAVAASSRGDARRVQALLAIEAVFANDLHEQDFTQVAATLQAYIAGKGAARQSVMAALAKPGAAAQAQAAQ

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	88.1
NLMSIM	70.0
AACOMP	92.6
Seqdif (SeqID)	36.9 (HEE9631150.1)
Structdif (F-Target)	6.0 (4im7 A)

ProtNLM

Name	Score
Mannitol dehydrogenase family protein	0.376
Fructuronate reductase	0.252
D-mannonate oxidoreductase	0.100
1.1.1.57	0.099
Polyol:NADP oxidoreductase	0.051
1.1.1.-	0.025