MEV8E

Prompt

3.5.4.4

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amidines. adenosine deaminase.

AI Generated Sequence

298 AAs
MTDLIRRAPKAHLEHHLDGSLRPETILELAAREGYDLPADDPEALAAWRAAAADCGSLERYLEIFDVHVAVMQTPEALARVAAECVEDLAADGVVYAEVRFAPEQHTAGGLDLDAVVEAVLDGFAAGEAAAGVRVRILAALMRHQGAASLEIAELAVEHRDRGVVGFDIAGPEAGFPPARFRPAFELARAAGLHLTIHAGEAFGAPSVWQAIELCGAERIGHGVRIIEDPALAAYVREKRIALELCPTSNVQTGAVASLAAHPFAALLDRGLRVTLNTDNRTVFSVTLNDELRLAAAA

Ligand/Cofactor

adenosine

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

Validation Metrics

PLDDT96.5
NLMSIM85.0
AACOMP86.3
Seqdif (SeqID)35.5 (WP_091090470.1)
Structdif (F-Target)4.8 (6n91 B)

ProtNLM

NameScore
Adenosine deaminase0.450
Adenosine aminohydrolase0.299
3.5.4.40.242
Adenine deaminase0.001
Aminodeoxyfutalosine deaminase0.001
Adenine aminohydrolase0.001
Designed by MP, using an AMD MI250 GPU
EC Repo - MEV8E | 310.ai