MA9KH

Prompt

2.1.1.228

Transferases. Transferring one-carbon groups. Methyltransferases. tRNA (guanine(37)-N(1))-methyltransferase.

AI Generated Sequence

300 AAs
MTFDVLTLFPEMFEGVLAHSIMGRAVKKGLLEVHTHNIRDFTTDKHRTVDDYPYGGGAGMVMKVEPLYAAIEAVKAERPETRVILMSPQGKPLTQAMVRELSQCEHIILICGHYEGIDQRVIDHLVTDEISIGDYVLSGGELAAMVLTDAVVRLLPGVLGNETSALQDSFADGLLDYPHYTRPAVWRDMDVPDVLLSGHHGRIARWRLEQSLKRTRERRPDLLEQAALSEADRKALAEFIREHHALYQMQHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT82.4
NLMSIM90.0
AACOMP81.0
Seqdif (SeqID)35.5 (HEY56967.1)
Structdif (F-Target)4.3 (8byh A)

ProtNLM

NameScore
TRNA [GM37] methyltransferase0.304
TRNA (guanine-N(1)-)-methyltransferase0.300
2.1.1.2280.228
M1G-methyltransferase0.161
TRNA (Guanosine(37)-N1)-methyltransferase TrmD0.002
TRNA0.000
Designed by MP, using an AMD MI250 GPU