MAPLI

Prompt

1.3.8.2

Oxidoreductases. Acting on the CH-CH group of donors. With a flavin as acceptor. 4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming).

AI Generated Sequence

299 AAs
MKAVIIGAGPIGGLAAIRLAQAGVPVTLLEKRDRPGGRAYVWEDDGFTFDAGPTVITDPYCLEELFALCGKDMADYVELLPVNPFYRLCWPDGTSFDYHSNDEAMKAQIEAFSPGDVAGYRRFLEYSRNVYEEGYKGLGVPFLDLSWDMFKAAPKLAKLQAWRSVYSMVSKFIKDERLRQAFSFHTLLVGGNPFATCSIYALIHALERDWGVWFARGGTHRLVQGMAKLAEELGGEIRLNEPVSEITLRGDRATGVVLADGTWQFADAVVSNADVVHTYRGLLPAHRGKAAAAAAAAAA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT90.5
NLMSIM70.0
AACOMP93.2
Seqdif (SeqID)31.7 (MDR6358431.1)
Structdif (F-Target)10.7 (4rep A)

ProtNLM

NameScore
Phytoene desaturase0.776
Phytoene dehydrogenase0.056
Phytoene desaturase (Neurosporene-forming)0.031
FAD-dependent oxidoreductase0.021
NAD(P)/FAD-dependent oxidoreductase0.016
1.14.99.-0.011
Designed by MP, using an AMD MI250 GPU