M9HLV

Prompt

1.6.3.1

Oxidoreductases. Acting on NADH or NADPH. With oxygen as acceptor. NAD(P)H oxidase (H2O2-forming).

AI Generated Sequence

565 AAs

MNWVINEGLSFVILVAWLGINLFLFFTRWYLYDEKKYFYYTRKILGSPLAWARASAACLNFNCMLILLPVCRNLLSFLRGSACCSSSRLRRQLDKNITFHKMVAWMIAFHTCIHTVAHLFNVERYHNSQVQDSGDLPKALSSLGDRPNETYLNPIRTFGNQPNTEVFFTTLPGVTGVIITICLALIITSSTEFIRRSNYEVFWYTHHLFVIFFIGLMIHGAGRIVRGQTPESLKVHNPDFCEKHLSEWGKDIDCPVPQFAGNPEMTWKWVIGPMLLYLCERLVRFWRSRQKVVISKVIMHPSKVLELQMKKKGFKMEPGQYIFIKCPAISKLEWHPFTLTSAPEEDYFSVHIRIVGDWTEALFKACGVEEFQKAWQLPRIAVDGPFGTASEDVFHYEVSMLVGAGIGVTPFASILKSVWYRYCKENTPLKLKKVYFYWLCRDTHAFEWFADLLQSLESQMEERGRANFLSYHIYLTGWDQSQAHVFAVHHDERDDVITGLKQKTLYGRPNWNEEFKSIAKNHPSTRVGVFLCGPKALAKTLHKKCNNYSSFDPRGVQFHYNKENF

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	86.3
NLMSIM	60.0
AACOMP	93.4
Seqdif (SeqID)	26.9 (XP_055123545.1)
Structdif (F-Target)	12.6 (8gz3 B)

ProtNLM

Name	Score
Cytochrome b-245 heavy chain	0.471
FAD-binding FR-type domain-containing protein	0.180
NADPH oxidase 3	0.121
Cytochrome b-245 heavy chain-like	0.042
NADPH oxidase 1	0.041
Cytochrome b-245 beta chain	0.017