M8DPE

Prompt

1.6.99.2

Oxidoreductases. Acting on NADH or NADPH. With other acceptors. Transferred entry: 1.6.5.2.

AI Generated Sequence

266 AAs

MSKIAIIGAGFAGLEAALKSCRELGLPKVTFEILTDRNVYLHWTNPLHPESGATIESSHIAIPYMRICFRPFNVEFRFPNLEHNIDYQKTIELAQERELKIYDYLVLTAGSCTNYFGTPEVTEAVHLTLSNEDAQKRFNDIVMAFCTGHLPNPELPELKSWFPITIVGGGHPTGLEYAAALADRRNVLVAGIGNISPDAAITIIDSAPRILRPAFPRSIWSAEEAFKRRGFDVMTRSRMVRYVKKNGLHITDGEFIETKMIWSAGV

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	77.6
NLMSIM	75.0
AACOMP	94.0
Seqdif (SeqID)	70.9 (MBI4491621.1)
Structdif (F-Target)	14.1 (5na4 A)

ProtNLM

Name	Score
Pyr_redox_2 domain-containing protein	0.757
Pyridine nucleotide-disulfide oxidoreductase	0.078
FAD-dependent oxidoreductase	0.073
NAD(P)/FAD-dependent oxidoreductase	0.032
FAD-dependent pyridine nucleotide-disulfide oxidoreductase	0.014
FAD-dependent pyridine nucleotide-disulphide oxidoreductase	0.005