M1QSO

Prompt

1.13.12.23

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases). 4-hydroxy-3-prenylbenzoate synthase.

AI Generated Sequence

500 AAs
MDLSTLTDLLDRFGDYASINLRRYKNVTVLDPENAEAILRTHDYDNPRMKKYVVDKIIYPQASIFTYDGSDHWRHLLKTKVKQFTLAAVSQFHVPLDEETLNRLMWLGDATSNGTSVDFWDEITQYGEIIGNTAVFGSLESMDENENEFYKALFEGSTAMISGLNDFLFPWTSFLPLNALKTLSSAFKVVANFADGFIKERMAEIKSGQLARDFLMVHNALYAAREGLALSDEEHVRQIQLDLLAGGQDTISATLTWTLFEIAKHPDIMQALRAEITAVFGARKPVTHQDLLKLQLYKDVIWEALRLHPVPSGIGRAVNEPCTLGGYIIPKGSRIALNVYAHNRDPNVFPNPDVFDPDRFLENLKGKVKLDFKFLPFGAGPRICPGMFLAYMELTMILAHVLQNFDLSLVPGDKVPVDERWLLPNGKVKLNFENLPFGAGPRICPGMFLAYLELTIVLAHLLQNFDLWLVPGDKVPVDDSWGFGLPKDKGILKVKSCRLA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT71.5
NLMSIM75.0
AACOMP94.2
Seqdif (SeqID)70.6 (OWM82269.1)
Structdif (F-Target)9.2 (4r21 A)

ProtNLM

NameScore
Cytochrome P4500.603
Cytochrome P450 monooxygenase0.089
Cytochrome p4500.069
Cytochrome p450 monooxygenase0.016
1.14.-.-0.012
Cytochrome P450,0.007
Designed by MP, using an AMD MI250 GPU