M4UA5

Prompt

2.5.1.21

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. squalene synthase.

AI Generated Sequence

528 AAs

MGLLKKLLGGLGHPGELRAILKWKVPFHAAHKRMDPKETPSLRRCYRYLDLQTRSFAAVIQALDPELRDVVCLFYLVLRGLDTIEDDMTIPLEVKKPLLRQFHQHLMEDGWTFTDNGPKEKDRQVLVDFQHICSEFAGMKPRYQVIIAKITDRMGNGMADYACHEATLGVQTIEDYDLYCDHYVAGLVGEGLSRLFVASGLAEPALLGQPELANSMGLFLQKTNIIRDYREDAEKGRRFWPREIWGKYVDEFEDLFKPENLDLALQCNSEMVLNALKHVEDCLFYMAALRNQSVFNFCAIPQVMAIATLELCFRNQAVFQKNVKIRKGQACQLIMESTQNLQVVCGIFRRYARKIHAKANPKDPNFLKISITCGRIQTKIEELFPTQPKAALAARLLSGKTPAEEAAKKALEAATWKDTLYFLMGVGGVLLAIVAGILIWAAMLGARFDLGWQELKGGNFRDPKGTQPQLLGGVLGKPAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FPP

CC(=CCCC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C)C

Validation Metrics

PLDDT	83.2
NLMSIM	90.0
AACOMP	89.8
Seqdif (SeqID)	38.9 (XP_040753474.1)
Structdif (F-Target)	2.8 (7wgi A)

ProtNLM

Name	Score
Squalene synthase	0.543
2.5.1.21	0.416
Farnesyl-diphosphate farnesyltransferase	0.010
Squalene synthase 1	0.003
Squalene synthase,	0.002
SQS	0.002