M2IOB

Prompt

1.1.1.18

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. inositol 2-dehydrogenase.

AI Generated Sequence

384 AAs

MTIRIGILGAGRIGQVHAANIAAHPDAELVAVADPFHERAAALAERHGARVYADVDAVLADPDVDAVLICSSTDTHAELIELAARAGKHVFCEKPVDLSLERIRACLDVVERSGVPLQIGFNRRFDPNFRALKARVEAGEIGEIQMLRITSRDPEPPPVEYVKVSGGLFRDMTIHDFDMARWIMGEEVEEVFATGSCLVDPAIGEAGDVDTAVVTLRFANGAMCTIDNSRRAVYGYDQRIEVFGSKGMLQVGNDRPTTVTLWSEAGALTDEPQYFFLERYRDAYAAEIAHFVDAVRDGRPPVVTGEDGLKALLLAEAAEKSLREGRPVRLDEILGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	83.4
NLMSIM	90.0
AACOMP	85.7
Seqdif (SeqID)	38.9 (HUU03756.1)
Structdif (F-Target)	8.0 (3ezy B)

ProtNLM

Name	Score
Inositol 2-dehydrogenase	0.587
1.1.1.18	0.263
Myo-inositol 2-dehydrogenase	0.048
Myo-inositol 2-dehydrogenase 1	0.020
Myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase	0.017
Myo-inositol 2-dehydrogenase/D-chiro-inositol 1-dehydrogenase	0.009