M48E6

Prompt

1.2.1.n2

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. fatty acyl-CoA reductase.

AI Generated Sequence

500 AAs

MSLPEFYEGKTFLITGATGFLGKVLIEKLLRSQPKVGKIYLLVRQPKGQTPEERFRELMNSKLFDFVREVHPEFKEKITAISGDVTEPNLGISDEDKESILESVNIVFHCAATVRFDERLQDAVQLNVTGTRQLLNFCKQMKNLEAFLHVSTAYVNCNRNLIEEVIYPPPVDPKKLIDSMEWLDETMTEITKPILRDRWPNTYFTKALAGEYVVQEYGDLNVAIIRPSIVGSSWKEPFPGWIDNFNGPSGLIFAAGKGILRTLMANDNTVADLIPVDVVVNTLLAAAWYAAVNRPKSNMVYNCTSTSQNPFNWGEVEGHVASSFKRFPLEQAFWRPANTITSNNLLYQWFSIVVSHVPALFYDILYRLTGRPTRMMKTVDRLHKVMTYLEYFTNRSWEFDTDNMERMLESMTPDERTFNFDVRTIDWDEYIENYILGTKKYILKEEMTDIPEKARNHLRNLRRYNYHFTFTIILVIWRILIARSQARQGRNWYCFVDSVY

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.8
NLMSIM	70.0
AACOMP	93.1
Seqdif (SeqID)	37.4 (XP_051048679.1)
Structdif (F-Target)	14.5 (7eoz B)

ProtNLM

Name	Score
Fatty acyl-CoA reductase	0.531
1.2.1.84	0.454
Fatty acyl-CoA reductase 1	0.005
Fatty acyl-CoA reductase 2	0.002
FACR1 reductase	0.001
Fatty acyl-CoA reductase 1-like	0.001