M42XX

Prompt

1.14.11.20

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors. deacetoxyvindoline 4-hydroxylase.

AI Generated Sequence

298 AAs

MEEVPVIDLSSLSSGDIERDKEVVEKIANACEKWGFFQVVNHGISLELLDEMKKVGKEFFELPMEEKLKYAKDPKGAVEGYGSKLQEKAGKELDWKEYTFFHHYPVSKNRYSYIPSKAPNQWPENPKGFREIMKEYAKEVKELAEKLLELLSENLGLEKGYFKKAMGDGNQFTLRINHYPPCPQPDLAIGVREHTDAGFLTILHQDQVGGLQVLKDGKWIDVKPIPNALVVNIGDQLEILSNGRYKSVLHRVIANKGKERMSIAFFCNPKLDAVIYPAPELVEEENPALYKEFTIKLQ

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	90.3
NLMSIM	75.0
AACOMP	89.8
Seqdif (SeqID)	50.0 (XP_027066052.1)
Structdif (F-Target)	10.4 (3oox B)

ProtNLM

Name	Score
Fe2OG dioxygenase domain-containing protein	0.548
1.14.20.6	0.091
1.14.11.61	0.044
Iron/ascorbate family oxidoreductase	0.026
Flavanone 3-dioxygenase	0.021
1-aminocyclopropane-1-carboxylate oxidase	0.019