M3M5Q

Prompt

1.13.99.3

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. Miscellaneous. tryptophan 2'-dioxygenase.

AI Generated Sequence

293 AAs
MTHPHPDVCIIGAGLAGLAAAYELARAGHRVTVLEARDRVGGRAWSEERFGEPCLEAGARLFVPFSQEEMFALCRELGLDLRRFHPDGRAFIRRDGRPFHLPLPGPWPALLARLEALGFDRLAAFEARGLPLPALEAAGLDAAALAARFGEPLTRYLWDCLYRGAVYADPAAASALDFDLAYAGGLGPWALASAAEGYALKVLEAGAAHYFRGGYQALIPKALAARCGGHVIRHTRVAAIERDGAVRVAATADGSAEFADAVIVAAPLALAHALAAPALPAAWAAALARLAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT73.2
NLMSIM60.0
AACOMP81.3
Seqdif (SeqID)50.0 (WP_086717457.1)
Structdif (F-Target)19.3 (5mog C)

ProtNLM

NameScore
FAD-dependent oxidoreductase0.633
Amino_oxidase domain-containing protein0.077
FAD-binding protein0.039
Protoporphyrinogen oxidase0.028
Amine oxidase0.028
NAD(P)/FAD-dependent oxidoreductase0.028
Designed by MP, using an AMD MI250 GPU