M0QIH

Prompt

1.14.99.29

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. Miscellaneous. deoxyhypusine monooxygenase.

AI Generated Sequence

295 AAs
MASPETIEALRNTLVDESKPLALRFRALFNLKNLACEDAIDAIAAAFTDPSALLKHELAYVLGQTRDPAAIPYLTQVLKDTKQEPMVRHEAAEALGALGDPKSLDILKQYMNDEPVEVRETCELAVDRIEWENSEGRKAETLKQSDYTSIDPAPPLPTESVPELEKKLLDTKLPLFQRYRAMFALRDIGTAEAVLALAKGFKDESALFRHEIAFVFGQLCHPASVPALTEALSNLKEAPMVRHEAAEALGSIADVEGVEDTLKALNDPEERVVRESVVALDMYAEFESSGEYQAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT85.4
NLMSIM80.0
AACOMP90.7
Seqdif (SeqID)35.2 (XP_025521525.1)
Structdif (F-Target)5.6 (4d4z A)

ProtNLM

NameScore
Deoxyhypusine monooxygenase0.287
DOHH0.239
Deoxyhypusine dioxygenase0.218
1.14.99.290.146
Deoxyhypusine hydroxylase0.098
Deoxyhypusine oxygenase0.001
Designed by MP, using an AMD MI250 GPU