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2 docs tagged with "attribute prediction"

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Protein Function Prediction: A Comprehensive Overview

Function prediction involves taking the amino acid sequence of a protein and determining what job(s) it performs. Proteins can act like tiny machines, and some important functions they do include speeding up (catalyzing) vital chemical reactions, moving (transporting) materials in and out of cells, or signaling when the body is under attack. Accurately predicting a protein’s function gives scientists valuable insights: they can identify what a newly discovered protein might do, search for proteins to perform specific tasks, or check if a computer-designed protein will work as expected. While experiments are necessary to confirm the function, comparing a protein sequence to known ones is a common first step.

ProtNLM for Predicting Protein Functions

Protein function prediction involves taking the amino acid sequence of a protein and determining what job(s) it performs. ProtNLM is an ML natural language model built on T5 for predicting the function(s) of a protein based on its amino acid sequence. Since proteins can have many different functions at the same time, multiple descriptions can be considered correct for the same input sequence. Accurately predicting a protein’s function gives scientists valuable insights: they can identify what a newly discovered protein might do, search for proteins to perform specific tasks, or check if a computer-designed protein will work as expected. While experiments are necessary to confirm the function, comparing a protein sequence to known ones is a common first step.