MCA20

Prompt

6.3.2.45

Ligases. Forming carbon-nitrogen bonds. Acid--amino-acid ligases.(peptide synthases). UDP-N-acetylmuramate L-alanyl-gamma-D-glutamyl-meso-2,6-

AI Generated Sequence

498 AAs

MTLSDLLSDLPLDLLSDLPLSLLSDLPLSLSSLSLDSRSVSPGSLFVALPGSRHGARFYADAALSGAVAVLADESGLSLDLPVLVVDDPRRALGAIASAFYGDPSRDMVVVGVTGTNGKTTTAYLIRQILDAAGLSTGLFSTVGTRFGDREIESLRTTPEPVDLQRMLADMAAAGVTHVAMEVSSHGLAQGRVDGLRFDVGVFTNLTRDHLDYHGTMEAYFAAKARLFTPSLRSRAVINLDDPWGRRLAEAARRRGVEVITYGLDGDADWRADDVEISSLGSSFTLRGPWGERAEVSLPLIGDFNVENALAAIGTIAAAGVDPAAAIEGLERFTGVPGRMEQVGGQGQFAVFVDYAHTPDALEKALTAVRPHTPGRLIVVFGCGGDRDRGKRPLMGEIAGRLADLVIVTDDNPRSEDPAAIRAEILAGAREAADGRPDAYREIGDRREAIRLAIEQARPGDVVLIAGKGHEDYQVIGKERRPWDDREVARRALLELGR

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	94.9
NLMSIM	85.0
AACOMP	91.3
Seqdif (SeqID)	43.7 (HYH34084.1)
Structdif (F-Target)	7.3 (4c12 A)

ProtNLM

Name	Score
Meso-diaminopimelate-adding enzyme	0.204
UDP-MurNAc-tripeptide synthetase	0.203
6.3.2.13	0.166
UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase	0.132
UDP-N-acetylmuramyl-tripeptide synthetase	0.105
Meso-A2pm-adding enzyme	0.097