MO24V

Prompt

1.1.1.17

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. mannitol-1-phosphate 5-dehydrogenase.

AI Generated Sequence

383 AAs

MKAVHFGAGNIGRGFIGKLLADAGVEVTFADVNQPLIDALNARHSYQVKVVGEGEQVETVRGVNAVNSIGPEVVDLIAETDLVTTAVGPKVLERIAPAIAKGLVKRKEQGNTSPLNIIACENMVRGTTQLKGHVFNHLPEDEKAWVESQVGFVDSAVDRIVPPSESATNDPLEVTVETFSEWIVDVTQFKGVLPNIPGMTLTDNLMAFVERKLFTLNTGHAITAYLGKLAGYQTIRDAILDESIRAQVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIQGIAAAMRYRSEDDPQAVELQALIAEKGPQAALAQITGLTDNSEVVSEVAATYNAMQK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.5
NLMSIM	80.0
AACOMP	94.7
Seqdif (SeqID)	11.3 (WP_000645421.1)
Structdif (F-Target)	1.2 (3h2z 2)

ProtNLM

Name	Score
Mannitol-1-phosphate 5-dehydrogenase	0.583
1.1.1.17	0.411
MPD	0.000
M1PDH	0.000
Inositol-3-phosphate synthase	0.000
Fructuronate reductase	0.000