MZCP2

Prompt

1.14.13.209

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. salicyloyl-CoA 5-hydroxylase.

AI Generated Sequence

473 AAs

MKLLLLGGGGYGAYRAALKLAKKYPELKLVDPRNYHLFTPMLHEVAAGTLDFDSIAVPIRGHFKRHNIHFYQGEVTAIDRAKKTVTLAPLEGEEGEEVPYDYLVVATGSVSTNFGVPGVKEHCFFLDTLDDAQKIHRKLLDCFELASVPLTDEERQRLLSFCIVGGGPTGVELAAELHDFVRDLDKYYPNIIKNNLKVTLIEAGPRILPMFKERLSAATQEQLTRKGVDIRLGTRMKEVTADGVVTKDGEFIPADTLVWSAGIQAPGFMKGLDGLEQNRNRILVTDTNLQVTGHDNIFAIGDCASCPDDGKFHLPTAQAAHQMGTFLAKNILARLEGKPLKPFEYKDKGSLASLGKYTAVADLMGWNLRGMPATWMKRAMYMYRSLGMRHRLRALGDWTKGLLFGDRISRIIPPPKLKFHDHKAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	90.8
NLMSIM	60.0
AACOMP	89.9
Seqdif (SeqID)	55.7 (MCD8548672.1)
Structdif (F-Target)	7.8 (5na4 A)

ProtNLM

Name	Score
Pyr_redox_2 domain-containing protein	0.152
NADH dehydrogenase,	0.151
NADH dehydrogenase	0.117
1.6.99.3	0.108
NAD(P)/FAD-dependent oxidoreductase	0.090
1.6.5.3	0.056