MZCHV

Prompt

2.7.1.197

Transferases. Transferring phosphorus-containing groups. Phosphotransferases.with an alcohol group as acceptor. protein-N(pi)-phosphohistidine--D-mannitol phosphotransferase.

AI Generated Sequence

500 AAs

MSSSLKVKVQNFGRFLSNMVMPNIGAFIAWGFITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADIPMFLGAMIAGPLGGWTIKHFDKWVDGKIKSGFEMLVNNFSAGIIGMLLAILAFLGIGPVVEALSKILAAGVNFLVVHNLLPLTSIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGLGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVIAGGMTGVFTLTILDGGLVSPASPGSILAVLAMTPKGAYFGNVAGIVAATAVSFVVASILLKTSKVKEEDDIEAATKRVQDMKAEKKGAAPLAAGGTVLDLSRVRKIIVACDAGMGSSAMGAGVLRKKVQDAGLQNISVTNSAINNLPDDVDLVITHRDLTERAMRQVPNAQHISLTNFLDSPLYNELTERLVAQRNENENEKVVSSLKDSFDDGSNHLFKLSAENI

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	84.2
NLMSIM	70.0
AACOMP	92.3
Seqdif (SeqID)	11.2 (ELK6113384.1)
Structdif (F-Target)	7.8 (1vrv A)

ProtNLM

Name	Score
Mannitol permease IIC component	0.211
PTS system mannitol-specific EIIB component	0.200
EIICBA-Mtl	0.179
Mannitol-specific phosphotransferase enzyme IIB component	0.139
PTS system mannitol-specific EIIC component	0.110
2.7.1.197	0.081