MZZ6M

Prompt

1.13.1.2

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor. Transferred entry: 1.13.11.2.

AI Generated Sequence

294 AAs
MKKHVVVIGGGFSGLETAKAAAKELGLKPNFEVLLDRNGGHWHFKPLLEHPASGTIESKVISEPYMRTLFSDFPFDFRYKEMKHIDTVEYIKTLAKKFDLKDYLIFATGSVKTKDFGNPGWEKWEITLTSLEDGQKIRRHVMNACARGHSWPDPEPLKKWPNFTIVGGGFHGVELAAEALPRVKKRTVVIGFNPSTDLITVSLIEGAPRILPAMSEKEYAKWVEELNKMGVDVVLTKRMTEYTENGLKITDGKWIETKMMFATGIQAKPFMPKMDGLPERNTVLDVDPNRLTTG

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT75.9
NLMSIM70.0
AACOMP91.3
Seqdif (SeqID)67.5 (MBI2743700.1)
Structdif (F-Target)14.0 (5kmq C)

ProtNLM

NameScore
Pyr_redox_2 domain-containing protein0.811
NAD(P)/FAD-dependent oxidoreductase0.055
FAD-dependent oxidoreductase0.039
Pyridine nucleotide-disulfide oxidoreductase0.032
NADH dehydrogenase0.010
FAD-dependent pyridine nucleotide-disulfide oxidoreductase0.008
Designed by MP, using an AMD MI250 GPU