MZMIC

Prompt

3.5.4.30

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amidines. dCTP deaminase (dUMP-forming).

AI Generated Sequence

247 AAs
MLLSDRDIRAEIDAGRVVIEPFDPAMVQPNSVDVRLDKYFRVFDNHKYPHIDPKEEQPDLTRLVEVEPDEPFILHPGEFVLASTYEVVSLPDDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVATLPIKLWPGMKIGQLCFFRLTSPAEHPYGSGRYGSKYQGQRGPTASRSHLNFHRTDIQIENANTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Ligand/Cofactor

dCTP

C1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O

Validation Metrics

PLDDT84.9
NLMSIM70.0
AACOMP80.9
Seqdif (SeqID)12.0 (WP_070350699.1)
Structdif (F-Target)2.2 (2qxx A)

ProtNLM

NameScore
DCD-DUT0.312
Bifunctional dCTP deaminase:dUTPase0.290
DCTP deaminase, dUMP-forming0.190
3.5.4.300.186
3.5.4.130.004
DCTP deaminase0.003
Designed by MP, using an AMD MI250 GPU
EC Repo - MZMIC | 310.ai