MZMH8

Prompt

1.1.1.23

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. histidinol dehydrogenase.

AI Generated Sequence

481 AAs

MPRILDTSAPDFAAAFAALLATKREDSADVDAVVAAIVADVRARGDAALVDYTRRFDRIDLTPAGIRVTAAEIDAAVAAADAATRAALELAADRIRAYHARQLPEDDRWTDALGAELGWRWTAVEAVGLYVPGGTASYPSSVLMNAVPARVAGVERIVMVVPAPGGRINPLVLAAARLAGVDEIWRIGGAQAVAALAHGTETIAPVDVIVGPGNAYVAAAKRHVFGTVGIDMIAGPSEILVIADADNDPDWIAADLLAQAEHDEAAQSILITDDAAFAAAVEAAVERQLETLPRAATAGASWRDFGAVILVPDLADAVPLADRIAAEHLELAVADPEALAARIRHAGAVFLGRHTPEAIGDYVGGSNHVLPTARSARFSSGLSVLDFVKRTSIARLGPEQLRALGPAAVALARAEGLEAHALSVAARLNLLGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.8
NLMSIM	85.0
AACOMP	83.5
Seqdif (SeqID)	21.7 (RIK85504.1)
Structdif (F-Target)	3.0 (4g09 2)

ProtNLM

Name	Score
HDH	0.391
Histidinol dehydrogenase	0.370
1.1.1.23	0.207
Histidinol-phosphate aminotransferase	0.010
Imidazole acetol-phosphate transaminase	0.003
2.6.1.9	0.002