MZMBK

Prompt

1.13.11.83

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. 4-hydroxy-3-prenylphenylpyruvate oxygenase.

AI Generated Sequence

421 AAs

MGPFPHDAPASITEANPMGTDGFEFVEFAHPEPETLGELFTRMGYTAVAKHRTKDITVWRQGDINIVLNAEPGSHAMRFVEEHGPCAPSMAWRVVDAKHAFDHAVAKGAEPYGEGKGPMELDAPAIVGIGGSLLYFIERYGEKGSAAYDAEFEWLGERDRNPVGAGLFYLDHLTHNVYRGNMDKWWDFYEKLFNFREIRFFDIEGKVTGLFSRAMTSPCGKIRIPINESKDDSQIAEYLKKYNGEGIQHIAVGTDDIYDATDRLAANGLKFMPGGPDTYYEMSYDRVNGHDEPIERMKKHGILIDGEGVVDGGMTKILLQIFSKTAIGPIFFEFIQRKGDDGFGEGNFRALFESIEEDQIRRGVLKVEEAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.9
NLMSIM	70.0
AACOMP	87.3
Seqdif (SeqID)	16.4 (WP_127370170.1)
Structdif (F-Target)	5.2 (1cjx D)

ProtNLM

Name	Score
4-hydroxyphenylpyruvate dioxygenase	0.825
1.13.11.27	0.149
4-hydroxyphenylpyruvate dioxygenase,	0.005
4-hydroxyphenylpyruvate dioxygenase 1	0.002
Hemolysin VllY	0.001
4-hydroxyphenylpyruvate dioxygenase, related	0.001