MZGPQ

Prompt

4.2.1.45

Lyases. Carbon-oxygen lyases. Hydro-lyases. CDP-glucose 4,6-dehydratase.

AI Generated Sequence

406 AAs

MTLPDLFAGKRVLVTGHTGFKGSWLTVWLLRLGAEVTGYALPPPTDPSLFDVAGLDARVHAVRGDITDRARLREVFAETEPDMVFHLAAQPLVRESYADPVETYETNVMGTVNLLEALRHAETVRCVVQVTTDKVYENHEWVWGYRENTELGGYDPYSNSKACSELVTASYRDSFFGAGRLAVTAARSGNVIGGGDFADDRILPDCVRAVAAGEPVTVRPWQHVLRPLQGYLELAERLYALGEAAAAGGGGAYWNFGPGEDAATTVRDVVRWLARRWGEGRGSVYDPAAAAAEHGHPEAHLLKLDCSKVAEALGWRPRWTLAEGIARTVEWYAALRRGEGMADCLEAQIRQYLAGRAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

CDP-glucose

C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O

Validation Metrics

PLDDT	85.1
NLMSIM	95.0
AACOMP	83.5
Seqdif (SeqID)	43.0 (MBI5919134.1)
Structdif (F-Target)	6.1 (1wvg 2)

ProtNLM

Name	Score
CDP-glucose 4,6-dehydratase	0.507
4.2.1.45	0.435
NAD(P)-bd_dom domain-containing protein	0.024
DTDP-glucose 4,6-dehydratase	0.003
GDP-mannose 4,6-dehydratase	0.001
CDP-glucose 4,6-dehydratase,	0.001