MZAHQ

Prompt

1.7.1.7

Oxidoreductases. Acting on other nitrogenous compounds as donors. With NAD(+) or NADP(+) as acceptor. GMP reductase.

AI Generated Sequence

209 AAs
MKIADLGGLKFDVLVAPRRSTILKSREVDLETRTFTFRHSKKTYTGIPMAAANMDTVGTFEMAQVLSGHMVFTAIHKPYTVEQWVDFAKEHPDVLDHVMASGSGSADDFEKLKAIIDAIPQLKFICLDVANGYTSHVFEFARKVRAKFPDTVIESGNVTGEAMTEQLILGAGIIRVGIGPGGSVCRTRVKGVDYPTQSAKVIEDAPHAG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT76.3
NLMSIM90.0
AACOMP92.8
Seqdif (SeqID)37.7 (XP_059206198.1)
Structdif (F-Target)11.9 (2a7r D)

ProtNLM

NameScore
GMP reductase0.608
1.7.1.70.220
Guanosine 5'-monophosphate oxidoreductase0.059
Guanosine monophosphate reductase0.043
IMPDH domain-containing protein0.026
GMP reductase 20.008
Designed by MP, using an AMD MI250 GPU